March 15 » Christopher Columbus returns to Spain after his first trip to the Americas.
May 4 » Pope Alexander VI divides the New World between Spain and Portugal along the Line of Demarcation.
September 26 » Pope Alexander VI issues the papal bull Dudum siquidem to the Spanish, extending the grant of new lands he made them in Inter caetera.
November 3 » Christopher Columbus first sights the island of Dominica in the Caribbean Sea.
November 18 » Christopher Columbus first sights the island now known as Puerto Rico.
November 19 » Christopher Columbus goes ashore on an island called Borinquen he first saw the day before. He names it San Juan Bautista (later renamed again Puerto Rico).
March 27 » Spanish explorer Juan Ponce de León reaches the northern end of The Bahamas on his first voyage to Florida.
April 30 » Edmund de la Pole, Yorkist pretender to the English throne, is executed on the orders of Henry VIII.
June 6 » Battle of Novara. In the Italian Wars, Swiss troops defeat the French under Louis II de la Trémoille, forcing them to abandon Milan; Duke Massimiliano Sforza is restored.
August 16 » Battle of the Spurs (Battle of Guinegate): King Henry VIII of England and his Imperial allies defeat French Forces who are then forced to retreat.
September 9 » James IV of Scotland is defeated and dies in the Battle of Flodden, ending Scotland's involvement in the War of the League of Cambrai.
September 25 » Spanish explorer Vasco Núñez de Balboa reaches what would become known as the Pacific Ocean.
When copying data from this family tree, please include a reference to the origin: Charles Olson, "Olson's Tree", database, Genealogy Online (https://www.genealogieonline.nl/olsons-tree/P12152.php : accessed January 11, 2026), "Antoinette de Bourbon-Vendome Duchess of Guise (1493-1583)".
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