February 12 » Santiago, Chile is founded by Pedro de Valdivia.
June 26 » Francisco Pizarro is assassinated in Lima by the son of his former companion and later antagonist, Diego de Almagro the younger. Almagro is later caught and executed.
August 23 » French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada.
September 13 » After three years of exile, John Calvin returns to Geneva to reform the church under a body of doctrine known as Calvinism.
September 30 » Spanish conquistador Hernando de Soto and his forces enter Tula territory in present-day western Arkansas, encountering fierce resistance.
December 10 » Thomas Culpeper and Francis Dereham are executed for having affairs with Catherine Howard, Queen of England and wife of Henry VIII.
When copying data from this family tree, please include a reference to the origin: John Layton, "Royal House of Layton of Stuart and Rohan", database, Genealogy Online (https://www.genealogieonline.nl/royal-house-of-layton-of-stuart-and-rohan/P627.php : accessed April 30, 2025), "Margaret TUDOR (1489-1541)".
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