April 7 » Francis Xavier leaves Lisbon on a mission to the Portuguese East Indies.
May 8 » Hernando de Soto stops near present-day Walls, Mississippi, and sees the Mississippi River (then known by the Spanish as Río de Espíritu Santo, the name given to it by Alonso Álvarez de Pineda in 1519).
June 26 » Francisco Pizarro is assassinated in Lima by the son of his former companion and later antagonist, Diego de Almagro the younger. Almagro is later caught and executed.
August 23 » French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada.
September 13 » After three years of exile, John Calvin returns to Geneva to reform the church under a body of doctrine known as Calvinism.
December 10 » Thomas Culpeper and Francis Dereham are executed for having affairs with Catherine Howard, Queen of England and wife of Henry VIII.
When copying data from this family tree, please include a reference to the origin: Jeremy Meyer, "Meyer Genealogy Tree", database, Genealogy Online (https://www.genealogieonline.nl/meyer-genealogy-tree/P512.php : accessed April 30, 2025), "Margaret Tudor (1489-1541)".
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