January 6 » The Catholic Monarchs Ferdinand and Isabella enter Granada at the conclusion of the Granada War.
April 17 » Spain and Christopher Columbus sign the Capitulations of Santa Fe for his voyage to Asia to acquire spices.
July 31 » The Jews are expelled from Spain when the Alhambra Decree takes effect.
September 6 » Christopher Columbus sails from La Gomera in the Canary Islands, his final port of call before crossing the Atlantic Ocean for the first time.
October 28 » Christopher Columbus lands in Cuba on his first voyage to the New World.
November 3 » Peace of Etaples between Henry VII of England and Charles VIII of France.
April 22 » Spanish conquistador Hernán Cortés establishes a settlement at Veracruz, Mexico.
June 28 » Charles V is elected Emperor of the Holy Roman Empire.
August 10 » Ferdinand Magellan's five ships set sail from Seville to circumnavigate the globe. The Basque second-in-command Juan Sebastián Elcano will complete the expedition after Magellan's death in the Philippines.
August 15 » Panama City, Panama is founded.
August 20 » Philosopher and general Wang Yangming defeats Zhu Chenhao, ending the Prince of Ning rebellion against the reign of the Ming dynasty's Zhengde Emperor.
September 20 » Ferdinand Magellan sets sail from Sanlúcar de Barrameda with about 270 men on his expedition to circumnavigate the globe.
When copying data from this family tree, please include a reference to the origin: Peter John Oswald, "Pop Oswald Tree", database, Genealogy Online (https://www.genealogieonline.nl/pop-oswald-tree/P30968.php : accessed December 5, 2025), "Lorenzo Ii of MEDICI (1492-1519)".
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