July 31 » The Jews are expelled from Spain when the Alhambra Decree takes effect.
August 3 » Christopher Columbus sets sail from Palos de la Frontera, Spain.
August 12 » Christopher Columbus arrives in the Canary Islands on his first voyage to the New World.
September 6 » Christopher Columbus sails from La Gomera in the Canary Islands, his final port of call before crossing the Atlantic Ocean for the first time.
December 5 » Christopher Columbus becomes the first European to set foot on the island of Hispaniola (now Haiti and the Dominican Republic).
December 25 » The carrack Santa María, commanded by Christopher Columbus, runs onto a reef off Haiti due to an improper watch.
March 4 » Hernán Cortés arrives in Mexico in search of the Aztec civilization and its wealth.
April 22 » Spanish conquistador Hernán Cortés establishes a settlement at Veracruz, Mexico.
August 10 » Ferdinand Magellan's five ships set sail from Seville to circumnavigate the globe. The Basque second-in-command Juan Sebastián Elcano will complete the expedition after Magellan's death in the Philippines.
August 15 » Panama City, Panama is founded.
August 20 » Philosopher and general Wang Yangming defeats Zhu Chenhao, ending the Prince of Ning rebellion against the reign of the Ming dynasty's Zhengde Emperor.
September 20 » Ferdinand Magellan sets sail from Sanlúcar de Barrameda with about 270 men on his expedition to circumnavigate the globe.
When copying data from this family tree, please include a reference to the origin: Peter John Oswald, "Pop Oswald Tree", database, Genealogy Online (https://www.genealogieonline.nl/pop-oswald-tree/P30968.php : accessed February 18, 2026), "Lorenzo Ii of MEDICI (1492-1519)".
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