April 7 » Francis Xavier leaves Lisbon on a mission to the Portuguese East Indies.
May 8 » Hernando de Soto stops near present-day Walls, Mississippi, and sees the Mississippi River (then known by the Spanish as Río de Espíritu Santo, the name given to it by Alonso Álvarez de Pineda in 1519).
June 26 » Francisco Pizarro is assassinated in Lima by the son of his former companion and later antagonist, Diego de Almagro the younger. Almagro is later caught and executed.
August 23 » French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada.
August 29 » The Ottoman Turks capture Buda, the capital of the Hungarian Kingdom.
September 30 » Spanish conquistador Hernando de Soto and his forces enter Tula territory in present-day western Arkansas, encountering fierce resistance.
April 27 » Cebu is established becoming the first Spanish settlement in the Philippines.
June 17 » Matsunaga Hisahide assassinates the 13th Ashikaga shōgun, Ashikaga Yoshiteru.
July 29 » The widowed Mary, Queen of Scots marries Henry Stuart, Lord Darnley, Duke of Albany, at Holyrood Palace, Edinburgh, Scotland.
August 28 » Pedro Menéndez de Avilés sights land near St. Augustine, Florida and founds the oldest continuously occupied European-established city in the continental United States.
September 8 » St. Augustine, Florida is founded by Spanish admiral and Florida's first governor, Pedro Menéndez de Avilés.
September 8 » The Knights of Malta lift the Ottoman siege of Malta that began on May 18.
When copying data from this family tree, please include a reference to the origin: Michael Jacobs, "Family tree Jacobs", database, Genealogy Online (https://www.genealogieonline.nl/stamboom-michael-jacobs/I48433.php : accessed February 11, 2026), "Joannes de Roo (1504-1565)".
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