She has/had a relationship with Carlos V de España.
Child(ren):
Isabella of Portugal ( 24 October 1503 – 1 May 1539) was the daughter of Manuel I of Portugal and Maria of Aragon. By her marriage to Charles V, Holy Roman Emperor, Isabella was also Holy Roman Empress and Queen consort of Aragon and Castile.
Isabella de Portugal | ||||||||||||||||||||||||||||||||||||||
Carlos V de España |
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