Buffalo is a town in Putnam County, West Virginia, along the Kanawha River. The population was 1,236 at the 2010 census. Buffalo is a part of the Huntington-Ashland, WV-KY-OH, Metropolitan Statistical Area (MSA). As of the 2010 census, the MSA had a population of 287,702. New definitions from February 28, 2013 placed the population at 363,000.