Paducah is a city in and the county seat of McCracken County, Kentucky, United States, and the largest city in the Jackson Purchase region. It is located at the confluence of the Tennessee River and the Ohio River, halfway between the metropolitan areas of St. Louis, Missouri, to the west and Nashville, Tennessee, to the east. The population was 25,024 at the 2010 census. Twenty blocks of the city's downtown have been placed on the National Register of Historic Places. Paducah is also the hub for the Paducah Micropolitan Area and the western Kentucky region, the Paducah micropolitan area includes McCracken, Ballard, and Livingston counties in Kentucky and Massac County in Illinois.