February 12 » Santiago, Chile is founded by Pedro de Valdivia.
April 7 » Francis Xavier leaves Lisbon on a mission to the Portuguese East Indies.
June 26 » Francisco Pizarro is assassinated in Lima by the son of his former companion and later antagonist, Diego de Almagro the younger. Almagro is later caught and executed.
August 23 » French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada.
September 30 » Spanish conquistador Hernando de Soto and his forces enter Tula territory in present-day western Arkansas, encountering fierce resistance.
December 10 » Thomas Culpeper and Francis Dereham are executed for having affairs with Catherine Howard, Queen of England and wife of Henry VIII.
When copying data from this family tree, please include a reference to the origin: Dr. Fermin DeLaFuente, "Fermin de la Fuente III, descendant from King Pelayo Balthes of Asturias", database, Genealogy Online (https://www.genealogieonline.nl/fermin-de-la-fuente-iii/P1339.php : accessed August 9, 2025), "Johanna Maria VanDer Ghenynst (1500-1541)".
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