March 4 » Hernán Cortés arrives in Mexico in search of the Aztec civilization and its wealth.
June 28 » Charles V is elected Emperor of the Holy Roman Empire.
August 15 » Panama City, Panama is founded.
August 20 » Philosopher and general Wang Yangming defeats Zhu Chenhao, ending the Prince of Ning rebellion against the reign of the Ming dynasty's Zhengde Emperor.
September 20 » Ferdinand Magellan sets sail from Sanlúcar de Barrameda with about 270 men on his expedition to circumnavigate the globe.
November 8 » Hernán Cortés enters Tenochtitlán and Aztec ruler Moctezuma welcomes him with a great celebration.
When copying data from this family tree, please include a reference to the origin: Stephen Clarke, "Clarke Family Tree", database, Genealogy Online (https://www.genealogieonline.nl/clarke-family-tree/I392494414012.php : accessed May 7, 2025), "Caterina Maria Romola di Lorenzo Médici (1519-1589)".
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